Are Medications for Premature Ejaculation Safe and Effective?

Imagine things are getting hot and steamy in the bedroom. Everything’s going just right—but suddenly, it happened again.

You came before you wanted it to be…

If you’ve found yourself in this situation more times than you’d like to admit, then you may be dealing with a medical condition known as Premature Ejaculation. A common sexual complaint affects as many as 1 out of 3 men at some point in their lives; it causes emotional distress and impacts a lot of relationships.

In this blog, we will walk you through premature ejaculation, its causes and remedies, and provide a discerning summary of what we can expect in the future.

What is Premature Ejaculation?

Premature ejaculation is more than just finishing quickly. It’s a condition where the climax happens too early during sexual intimacy, often with little stimulation. Typically, this means reaching climax within one minute of penetration, though the exact timing can vary. 

Understanding this condition also means looking at how it affects relationships and emotions, giving a fuller picture of its impact.

What Happens in Premature Ejaculation?

Step 1 → Heightened Arousal

Men with premature ejaculation often experience intense reactions to visual, physical, or emotional stimuli, leading to a quicker arousal phase.

Step 2 → Hyperexcitability

This heightened sensitivity in the genital area can make it challenging to control arousal levels.

Step 3 → Short Plateau Phase

The phase where sexual tension builds before ejaculation is shorter in men with PE, giving the body less time to adjust. Due to high sensitivity, tension rises quickly, moving the body toward ejaculation at a faster pace.

Step 4 → Nervous System Role

The sympathetic nervous system plays a crucial role, and in men with PE, it may be overactive, contributing to rapid ejaculation. 

Step 4 → Early Ejaculation Reflex

Reaching the peak of arousal too quickly triggers the ejaculatory reflex early, leading to quick release. 

Result → Emotional strain, impacting relationship satisfaction. 

Some men even avoid intimacy due to past experiences, affecting their connection with their partners.

What Causes Premature Ejaculation?

The causes of premature ejaculation can be many. It may result from psychological, biological, or lifestyle factors—or a combination of these.

Psychological Factors

Mental Health

The psychological roots of premature ejaculation are often tied to depression, anxiety, low self-esteem or performance pressure. Worries about not meeting expectations can trigger a chain reaction, leading to an early climax.

Relationship Issues

Intimate relationships play a big role in sexual health. When there’s tension, unresolved conflict, or emotional distance, it can contribute to premature ejaculation. 

Negative Feelings About Intimacy

Poor body image, guilt, or negative experiences related to intimacy can create a mental environment that also causes premature ejaculation.

Conditioning from Early Experiences

Early sexual experiences that were rushed or associated with anxiety may condition a man to ejaculate quickly in future encounters.

Biological Factors

Hormonal Imbalances

Abnormal levels of neurotransmitters (such as serotonin and dopamine) and hormones (like prolactin, luteinizing hormone (LH), and thyroid-stimulating hormone (TSH)) can influence ejaculation timing. Low serotonin levels are particularly linked to shorter ejaculation times.

Medical Conditions

Certain health issues, such as prostate problems, thyroid disorders, and diabetes, may contribute to PE by affecting hormonal balance or nerve function.

Erectile Dysfunction (ED)

Men with ED may develop PE as they rush to ejaculate due to anxiety about maintaining an erection.

Genetics

There may be a hereditary component to PE, with some men more predisposed due to family history. Genetic causes related to the molecules that signal between nerves may lead to PE.

Neurological Disorders

Conditions affecting nerve function, such as multiple sclerosis or neuropathy, can also play a role in premature ejaculation.

Lifestyle factors

Substance Use

Alcohol and recreational drugs can impair sexual function and increase the likelihood of experiencing PE.

Obesity and Metabolic Syndrome

Conditions like metabolic syndrome, characterized by obesity, high blood pressure, and insulin resistance, have been associated with increased rates of PE. 

Physical Inactivity

A sedentary lifestyle can reduce blood flow, including the pelvic region. This decreased circulation can negatively affect erectile function and ejaculation control, as proper blood flow is crucial for sexual arousal and performance. Also, it can lead to lower testosterone levels, potentially leading to PE.

Also, less active men may develop a pattern of rushing through sexual encounters due to anxiety or discomfort with their bodies. This behavioral conditioning can reinforce the habit of premature ejaculation over time.

Primary and Secondary Ejaculation

Premature ejaculation (PE) is classified into two main types: primary (lifelong) PE and secondary (acquired) PE. 

How to Diagnose PE?

There is no specific test to diagnose PE.

A doctor can diagnose premature ejaculation (PE) by asking questions about:

Self-Assessment of Symptoms

PE is generally recognized by a pattern of ejaculation within about one minute of penetration or earlier than desired. Symptoms of PE also include feeling unable to delay ejaculation during sexual activity and experiencing distress or frustration because of it.

Medical History & Sexual History

Your doctor may ask detailed questions about the patient’s medical history to rule out other conditions like prostate issues, nerve sensitivity, or hormonal imbalances that might contribute to PE. 

They may also ask about your sexual history and past experiences, like 

• How long has the patient been experiencing PE?
• Does this occur in all sexual encounters or only with certain partners?
• How quickly does ejaculation occur after penetration?

Physical Exam

In some cases, a physical exam may be done to check for any physical abnormalities or health issues. The doctor may look for signs of penile or testicular issues or check for other potential conditions affecting sexual function.

Use of Diagnostic Criteria

The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) provides specific criteria for diagnosing PE:

• Ejaculation occurs within approximately one minute following vaginal penetration during partnered sexual activity.
• The symptoms have persisted for at least six months.
• The condition causes clinically significant distress.
• The dysfunction cannot be better explained by nonsexual mental disorders, medical conditions, or severe relationship distress.

Questionnaires and Diagnostic Tools

Some healthcare providers use PE-specific questionnaires to assess severity, such as the Premature Ejaculation Diagnostic Tool (PEDT). This tool helps determine if your experiences align with clinical definitions of PE.

For example: 

Score yourself from 0 to 4, where 0 represents Not at all (0%) and 4 represents Extremely difficult (100%)

• How difficult is it for you to delay ejaculation?
• Do you ejaculate before you want to?
• Do you ejaculate with very little stimulation?
• Do you feel frustrated because of ejaculating before you want to?
• How concerned are you that your time to ejaculation leaves your partner unfulfilled?

You may be asked to fill out other surveys regarding emotional and relational impacts to help tailor the treatment plan.

Follow-Up with a Specialist (If Needed)

If the diagnosis isn’t clear or if PE persists despite initial treatments, you might be referred to a urologist or psychologist. They can conduct more specialized evaluations and discuss options for therapy or medication.

How to Stop Premature Ejaculation (PE)?

Here are some effective strategies to help prevent premature ejaculation (PE) through simple techniques and lifestyle changes:

Behavioral Techniques for PE

Start-Stop Method

Stimulate the penile organ until close to ejaculation, then pause until the urge subsides. Repeat several times to build control and recognize sensations that lead to ejaculation.

Squeeze Technique

Similar to the Start-stop method, this technique, when one is near ejaculation, squeezes the head of the penile organ to reduce arousal. After a short pause, resume the stimulation.

Masturbation Before Intercourse

Masturbate 1–2 hours before intimacy to use the natural refractory period and help delay ejaculation during intercourse.

Pelvic Floor Exercises (Kegel Exercises)

Strengthen the pelvic muscles by contracting the muscles used to stop urination for a few seconds, then release. Do three sets of 10 reps daily to improve ejaculatory control.

Distracted Thinking

When nearing ejaculation, divert your thoughts to non-sexual topics. This mental distraction can help delay the climax.

Masturbation Techniques

Practice masturbation without lubrication to increase sensitivity awareness and learn to control the urge to ejaculate.

Also, experiment with different types of stimulation (e.g., speed or pressure) during masturbation to find what helps maintain arousal while delaying ejaculation.

Cognitive Behavioral Therapy (CBT)

Focus on identifying and changing thought patterns that contribute to anxiety and quick arousal, helping build better control over ejaculation.

Physical Aids

Condoms

Use thicker condoms or those with mild numbing agents to decrease sensitivity, helping prolong the time before ejaculation.

Try a different position

Switching to various positions, such as female superior, doggy style, knees position, and side-to-side, can help with premature ejaculation. These positions place less strain on the penile organ, which may naturally delay ejaculation and extend the sexual experience.

Medication For Premature Ejaculation

Topical Anesthetic Creams, Gels, or Sprays

Apply products (Lidocaine, Prilocaine, or Lignocaine-based) to reduce penile sensitivity and delay ejaculation. 

Pills For Premature Ejaculation

SSRIs (Selective Serotonin Reuptake Inhibitors)

Dapoxetine and Sertraline for premature ejaculation can help delay ejaculation. They work by increasing the neurotransmitter serotonin levels in the brain. They basically block the serotonin transporters, inhibiting the reuptake of serotonin, hence better control over ejaculation.

Phosphodiesterase-5 Inhibitors

Medications like sildenafil or tadalafil may help in premature ejaculation treatment if PE is associated with erectile dysfunction.

Lifestyle Changes

Regular Exercise

Physical activity can improve overall health, reduce stress, and enhance sexual function.

Healthy Diet

A balanced diet supports overall well-being, which can positively impact sexual health. Include foods rich in zinc and magnesium, which may support reproductive health and help with PE symptoms.

Avoiding Alcohol and Drugs

Reducing or stopping alcohol and recreational drug use can improve sexual performance and control over ejaculation.

Stress Management

Practice deep breathing, mindfulness, or relaxation exercises to manage performance anxiety and improve control.

Supplements for Premature Ejaculation

Zinc

Zinc is crucial for testosterone production and overall male reproductive health. Low levels of zinc have been associated with sexual dysfunction. Therefore, supplementation with zinc may improve testosterone levels and support prostate health, which can be beneficial for ejaculatory control.

Vitamin B12

Vitamin B12 is vital for nerve function and red blood cell production. Deficiencies in B12 have been linked to sexual dysfunction. Some studies indicate that men with PE may have lower levels of B12, suggesting that supplementation could help improve symptoms.  (Source: Andrologia)

Vitamin D

Low serum vitamin D levels are associated with an increased risk of acquired PE. Supplementation may help improve sexual health and ejaculatory control. (Source: Journal of Men’s Health)

Magnesium

Magnesium is another mineral important for healthy reproductive health & sperm production. According to a study published in the Asian Journal of Andrology, low magnesium levels can contribute to premature ejaculation by increasing muscle contractions involved in orgasms. Having enough magnesium in your diet may also help manage this condition.

Ginseng

Ginseng is a traditional herbal remedy known for its potential to enhance energy and reduce fatigue. Some studies suggest ginseng may improve sexual performance and satisfaction, though more research is needed specifically on its effects on PE.

Foods to cure premature ejaculation

Alternative to over-the-counter treatments, lifestyle changes, behavioral therapies, and prescription PE medicine for premature ejaculation, the best foods to cure premature ejaculation & help you perform better are:

FAQs on Premature Ejaculation

What are the reasons for premature ejaculation?

Premature ejaculation can be caused by various factors, including

• Psychological Factors (Anxiety, stress, depression, and negative past sexual experiences)
• Biological Factors (Hormonal imbalances, neurotransmitter irregularities (especially serotonin), and certain medical conditions (like diabetes or prostate issues))
• Lifestyle Factors (Substance abuse (alcohol and recreational drugs), lack of physical activity, and poor overall health)

How can I cure my premature ejaculation?

There are several effective treatments for premature ejaculation. These include

• Behavioral techniques (like the start-stop method)
• Pelvic floor exercises
• Counseling 
• Medical options like topical anesthetic creams, oral medications, and natural supplements may also help.

Can you get pregnant by premature ejaculation?

Yes, pregnancy is possible with premature ejaculation if sperm is present in the ejaculate and enters the vagina. Even a single drop of semen can contain enough sperm to fertilize an egg. Pre-ejaculate (precum) also contains sperm (in smaller amounts), so using contraception is recommended if pregnancy is not desired.

Does premature ejaculation have sperm?

Premature ejaculation ejaculate can contain sperm. While the primary ejaculate (the fluid released during orgasm) has a higher concentration of sperm, pre-ejaculate fluid may also contain viable sperm. Therefore, even if ejaculation occurs prematurely, there is still a risk of pregnancy.

What is the best med for premature ejaculation?

The best medication for PE often depends on individual circumstances. Commonly recommended options include:

• Dapoxetine (Priligy)
• Other SSRIs (Medications like paroxetine, fluoxetine, or sertraline)
• Topical Anesthetics (Creams or sprays containing lidocaine or prilocaine)
• Phosphodiesterase-5 Inhibitors (Medications like sildenafil (Viagra))

Consult a healthcare professional to find the best option based on individual needs.

Conclusion

Throughout this exploration of premature ejaculation (PE), we have examined the various aspects that lead to this prevalent sexual issue. The interaction of psychological, physiological, and interpersonal components is one of the main points. Premature ejaculation is influenced by a complicated network of causes, including neurological concerns, relationship problems, stress, and anxiety.

Although the path to stop premature ejaculation may appear complicated, things can get better. Many people have successful outcomes when the proper therapies and interventions are combined. When recommended by a medical practitioner, medication, behavioral therapy, and lifestyle changes have all been proven successful in controlling and even curing PE. Knowing the essential aspects, getting professional assistance, and hoping for better.